On the contrary, in lung squamous carcinoma, while most of the m5C-regulators showed significantly different expression between tumor and normal samples, only NSUN3 could significantly predict prognosis (and NSUN4 almost significantly) ( Pan et al., 2021 ).
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An m5C methylation regulator-associated signature predicts prognosis and therapy response in pancreatic cancer.
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The sentences
The m5C-score represented a highly significant independent prognostic marker.