The crosstalk between MYC and mTORC1 during osteoclastogenesis.

Nonetheless, the level of CTX-I, a serum bone resorption marker, exhibited a decreasing trend in TSC2 ∆OC mice compared to WT mice ( Figure 4F ), indicating that osteoclasts from TSC2 ∆OC mice exhibited an attenuated resorbing function and caused increased bone mass.

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