Downregulation of Elovl5 promotes breast cancer metastasis through a lipid-droplet accumulation-mediated induction of TGF-β receptors.

Cell Death Dis · 2022 · PMC9440092 · PMID 36056008

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an increasing trendno p-value reported

However, the increase of LD abundance is more frequently correlated with an aggressive cancer [ 38 – 41 ] and breast cancer cell lines show an increasing trend in LD content when going from the non-malignant MCF10A cells, to the intermediately aggressive MCF-7 cells to the highly aggressive MDA-MB-231 cells [ 42 ].

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