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Modelling intramuscular drug fate <i>in vitro</i> with tissue-relevant biomimetic hydrogels.

Int J Pharm X · 2022 · PMC9440386 · PMID 36065415

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Whilst PS20 generally reduced the release of all GFP variants in all hydrogels, such stabilisation may be significant for strongly negative macromolecules: GFP-neg formulated with PS20 in Col1/HA hydrogels exhibited expedited diffusion away from the injection site ( Fig. 7 C).

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