Barely Significant
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The effect of exercise interventions on Irisin level: a systematic review and meta-analysis of randomized controlled trials.

EXCLI J · 2022 · PMC9441678 · PMID 36110558

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a trend toward significanceno p-value reported
(2015[ 63 ]) studied the impacts of long-term exercise on circulating irisin in adults; the results revealed that chronic resistance training had a moderate and significant effect in reducing irisin compared with the control group, while endurance exercise only had a trend toward significance.

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