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Pharmacokinetics of baicalin and oroxyloside in plasma and different tissues of rats after transnasal aerosol inhalation and intravenous injection of Tanreqing.

Front Pharmacol · 2022 · PMC9442038 · PMID 36071852

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an increasing trendno p-value reported
The mean area under the curve (AUC 0-∞ ) of BAI (226.565 h·ng/ml) after medium dose TI of TRQ was slightly lower than that after low dose TI (257.171 h·ng/ml), but the AUC 0-∞ showed an increasing trend with the increase of TI doses in the range of 0.03-0.12 ml/kg ( Figure 5B ).

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