A gene set enrichment analysis (GSEA) of the target candidates, compared to sets of commonly up‐ and downregulated genes, revealed a highly significant role for candidate genes in Developmental Biology and processes linked to the regulation of transcription (Fig 1E ), in line with the known roles of miRNAs in early development and stem cells (DeVeale et al , 2021 ).
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Global and precise identification of functional miRNA targets in mESCs by integrative analysis.
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