Barely Significant
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Circ0007042 alleviates intervertebral disc degeneration by adsorbing miR-369 to upregulate BMP2 and activate the PI3K/AKt pathway.

Arthritis Res Ther · 2022 · PMC9446735 · PMID 36068615

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hedged sentence
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closest p · 0.2× alpha
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boldest claim

The sentences

extremely significantP< 0.01actually significant
Among the three designed siRNAs, siRNA2 had the most significant inhibitory effect on the expression of the BMP2 gene, and the difference was extremely significant compared with the control group ( P< 0.01).

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