Pharmacokinetic assessment of vancomycin in critically ill patients and nephrotoxicity prediction using individualized pharmacokinetic parameters.

Also, there was a highly significant association ( p -value <0.0001) between each trough concentration, peak concentration, AUCτ, AUC 24h , Cl, V d with AKI occurrence, which indicates that these pharmacokinetic parameters would be considered as suitable parameters in vancomycin-induced AKI prediction.

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