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NMR Reveals Functionally Relevant Thermally Induced Structural Changes within the Native Ensemble of G-CSF.

Mol Pharm · 2022 · PMC9449972 · PMID 35948076

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may be significantno p-value reported
5 , 7 , 8 Finally, we revealed subtle conformational changes in binding site III residues that may be significant in preorganizing the active site for receptor binding.

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