The SREBP-dependent regulation of cyclin D1 coordinates cell proliferation and lipid synthesis.

Front Oncol · 2022 · PMC9451027 · PMID 36091143

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failed to reach significanceno p-value reported

Inactivation of SREBP1 in HepG2 cells also resulted in a reduction in cyclin D1 mRNA, while the effect of SREBP2 inactivation failed to reach significance ( Figure 1D ).

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