Real-life Effectiveness and Safety of Risankizumab in Moderate-to-severe Plaque Psoriasis: A 40-week Multicentric Retrospective Study.

Acta Derm Venereol · 2021 · PMC9455321 · PMID 34596230

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.0510

boldest claim

The sentences

of borderline significancep = 0.051so close (0.05 < p ≤ 0.1)

Despite the negative association between cardiometabolic comorbidities, such as obesity, hypertension, diabetes, etc., and PASI 100 response of borderline significance ( p = 0.051), no statistically significant association was found with the percentage of patients with or without CMC achieving PASI 75/90/100 at weeks 16 or 40.

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borderline significancep = 0.051so close (0.05 < p ≤ 0.1)

Logistic regression showed, with a borderline significance, that patients with CMC had lower odds of reaching PASI 100 at week 40 compared with those without CMC (odds ratio (OR) 0.38, 95% CI 0.14–1.00, p = 0.051).

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