highly significantp < 0.001
Effect of Long-Term Increased S100B Levels on Hippocampal Progenitor Cell Proliferation and Migration The comparison of the proliferative marker BrdU and Ki67 for quantification of progenitor cell proliferation revealed that both markers provided highly significant congruent results ( Figure 1 A; BrdU mean 2.33 ± 2.99 immunoreactive cells; F 5,210 = 33.91, p < 0.001; Ki67 mean 1.53 ± 2.90 immunoreactive cells; F 5,206 = 73.49, p < 0.001; r = 0.608, p < 0.001).