Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer's-induced retinal vasculopathy by limiting Clec7a/Galectin-3<sup>+</sup> neurodegenerative microglia.

Acta Neuropathol Commun · 2022 · PMC9461176 · PMID 36076283

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a nonsignificant trendno p-value reported

Stereological quantification uncovered a prominent downregulation of retinal vascular ZO-1 in 8-month-old APP/PS1 mice versus WT controls, while miR-155cKO displayed a nonsignificant trend of restoring retinal vascular ZO-1 expression (Fig. 5 e).

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Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer's-induced retinal vasculopathy by limiting Clec7a/Galectin-3&lt;sup&gt;+&lt;/sup&gt; neurodegenerative microglia.

The sentences

Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer's-induced retinal vasculopathy by limiting Clec7a/Galectin-3<sup>+</sup> neurodegenerative microglia.