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Evaluating the national system for rare diseases in China from the point of drug access: progress and challenges.

Orphanet J Rare Dis · 2022 · PMC9463840 · PMID 36088349

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an increasing trendno p-value reported
In addition, hospital-level availability of drugs in all efficacy groups showed an increasing trend year by year.

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a decreasing trendno p-value reported
It has been reported that the median DDDc of orphan drugs in China showed a decreasing trend from 2010 to 2017, which is different from our finding [ 15 ].

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.