S-nitroso-L-cysteine stereoselectively blunts the adverse effects of morphine on breathing and arterial blood gas chemistry while promoting analgesia.

As such, conditions and disease states that favor the formation or degradation of S-nitrosothiols [ 2 , 18 , 23 , 31 , 105 , 108 , 117 , 187 ] may be significant for determining the efficacy of the pharmacological actions of opioids.

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