While these data suggest an overall trend of TGF-β-mediated upregulation of ST6Gal1, it is important to recognize that not all cells have been reported to increase ST6Gal1 levels in response to TGF-β treatment: in HCV29 bladder epithelial cells, TGF-β decreased expression of ST6Gal1 ( Guo et al., 2014 ).
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