A majority of the differentially expressed genes, 2451 total, including the highly significant Il2ra, Shmt1, Cish, Tbx21, Tnfsf8, Tnfsf9, and Smalf1 were upregulated in both WT and Cd47 −/− CD8+ T cells ( Figure 2g , Data S1, S2).
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Loss of CD47 alters CD8+ T cell activation <i>in vitro</i> and immunodynamics in mice.
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