an increasing trendp < 0.01
N4PB analysis revealed statistically significant differences in mean plasma GFAP and NfL, and CSF NfL levels with an increasing trend between normal controls, IPD<2 yrs to onset, sIPD, and CJD cohorts (p < 0.01).
N4PB analysis revealed statistically significant differences in mean plasma GFAP and NfL, and CSF NfL levels with an increasing trend between normal controls, IPD<2 yrs to onset, sIPD, and CJD cohorts (p < 0.01).
Age effect reflects a biological process linked to aging, effect of period of death shows an overall trend such as diagnosis evolution, and a cohort of birth effect reflects an environmental exposure change.