2 F); however, this observed increase in IL-6 approached but did not reach significance.
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Systemic interleukin-6 inhibition ameliorates acute neuropsychiatric phenotypes in a murine model of acute lung injury.
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B However, in the hippocampus there was a trend toward significance, with α-IL-6 treated animals have lower CC3.
There were corresponding significant changes in amygdalar and hippocampal IL-6 and TNF-α, and a nonsignificant trend toward decreased IL-1β expression in the IL-6 inhibited compared to the saline-treated groups in both brain regions (F i g. 4 D–I).