of borderline significancep = 0.052
When these loci were used as genetic instruments vs genetic data for glycine, glycerate or lactate (the only metabolites for which GWAS data were found), evidence was found for an association between shared genes between MetS and glycine (IVW beta 0.021, SE 0.007, p = 0.0027), but not for glycerate (IVW beta -0.0025, SE 0.006, p = 0.71), while lactate was of borderline significance (IVW beta 0.012, SE 0.006, p = 0.052).