Heterozygous LRP1 deficiency causes developmental dysplasia of the hip by impairing triradiate chondrocytes differentiation due to inhibition of autophagy.

Proc Natl Acad Sci U S A · 2022 · PMC9477389 · PMID 36067312

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highly significantno p-value reported

A highly significant boost came for the field of WNT signaling with the discovery of LRPs as WNT coreceptors for WNT/β-catenin signaling since 2000 ( 84 – 86 ).

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