Nicotine self-administration and ERK signaling are altered in RasGRF2 knockout mice.

Front Pharmacol · 2022 · PMC9479000 · PMID 36120353

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failed to reach significanceno p-value reported

RasGRF2 KO mice failed to show this increase in the ventral or dorsal striatum, although in the dorsal striatum there was a modest increase in pERK1/2 that failed to reach significance, due to a single animal showing a high pERK1/2 expression following nicotine administration.

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