Both YAP1-MAML2 and constitutively active YAP1 drive the formation of tumors that resemble NF2 mutant meningiomas in mice.

Both conditions shared a highly significant overlap in their DEGs (396 overlapping up-regulated and 445 down-regulated DEGs; P < 10 −314 for both comparisons) and similarly regulated several direct YAP1 downstream target genes ( Supplemental Fig.

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