Inhibition of APOC1 promotes the transformation of M2 into M1 macrophages via the ferroptosis pathway and enhances anti-PD1 immunotherapy in hepatocellular carcinoma based on single-cell RNA sequencing.

Redox Biol · 2022 · PMC9482117 · PMID 36108528

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an increasing trendno p-value reported

The results indicated that the relative proportion of M2 macrophages, B cells, and CD4 T cells in the APOC1 −/− group exhibited a downward trend than the WT group, whereas CD8 T cells, M1 macrophages, and NK cells exhibited an increasing trend ( Fig. 6 B–C).

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