A combined spatial score of granzyme B and CD68 surpasses CD8 as an independent prognostic factor in TNM stage II colorectal cancer.

BMC Cancer · 2022 · PMC9482175 · PMID 36114487

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0010

boldest claim

The sentences

highly significantp < 0.001actually significant

Within the tumour centre, comparison of TP zones with varying radii around the tumour revealed the largest number of highly significant associations ( p < 0.001) for the TP25μm zone.

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a weak trendno p-value reported

Regarding the prognostic value of tumour proximity (TP) zones with varying radii around the tumour in this study, only a weak trend could be observed with the TP25μm zone presenting the lowest hazard ratios in both cohorts.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.