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α2-macroglobulin-rich serum as a master inhibitor of inflammatory factors attenuates cartilage degeneration in a mini pig model of osteoarthritis induced by "idealized" anterior cruciate ligament reconstruction.

Front Pharmacol · 2022 · PMC9483147 · PMID 36133821

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a decreasing trendno p-value reported
Gait assessment Across all groups, the ratios of all gait parameters of the left hind limb to those of the right hind limb initially showed an increasing trend, followed by a decreasing trend, except in the IACL-R group, which showed another increasing trend toward the end.

also in 47,180 other papers

an increasing trendno p-value reported
The IL-2 concentration in the IACL-R group subsequently showed an increasing trend from day 30 to day 90.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.