Although not significant, a decreasing trend was also observed in the frequency of IFN-γ + and IL-2 producing CD4 + T-cells ( Figures 7B , C ).
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Evaluation of the immunomodulatory effects of interleukin-10 on peripheral blood immune cells of COVID-19 patients: Implication for COVID-19 therapy.
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IL-10, GM-CSF, and IL-6 increased later and showed an increasing trend over time.