Biomarkers for efficacy of adjuvant chemotherapy following complete resection in NSCLC stages I-IIIA.

Eur Respir Rev · 2015 · PMC9487808 · PMID 26028645

Europe PMC DOI

hedged sentence

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

nearly reached significancep=0.07so close (0.05 < p ≤ 0.1)

TUBB3 High expression of TUBB3 (high was defined as greater than the median H-score) predicted significantly longer DFS in patients treated with cisplatin-based ACT compared with controls (HR 0.45, 95% CI 0.27–0.75; p=0.002) and nearly reached significance for better OS (HR 0.64, 95% CI 0.39–1.04; p=0.07) [ 14 ].

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