Supplemental oxygen and dypsnoea in interstitial lung disease: absence of evidence is not evidence of absence.

In a single-blinded randomised crossover study, the authors demonstrated that breathing oxygen at inspiratory oxygen fraction ( F IO 2 ) 60% during a constant load cycle ergometer test resulted in decreased dyspnoea at iso-time (mean 1.9 Borg units), as well as a highly significant increase in endurance time (mean 10.3 min).

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