Barely Significant
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Genetically predicted circulating levels of glycine, glutamate, and serotonin in relation to the risks of three major neurodegenerative diseases: A Mendelian randomization analysis.

Front Aging Neurosci · 2022 · PMC9490425 · PMID 36158554

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a decreasing trendno p-value reported
In a study based on the European-wide AddNeuroMed/Dementia Case Register biobank repositories (n = 354), a decreasing trend in serum concentrations of serotonin was reported in line with clinical classification, namely the elderly control, mild cognitive impairment and AD ( Whiley et al., 2021 ).

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