Abstinence-Dependent Effects of Long-Access Cocaine Self-Administration on Nucleus Accumbens Astrocytes Are Observed in Male, But Not Female, Rats.

Although PSD-95-positive pixels from rats that underwent prolonged abstinence from LgA cocaine self-administration exhibit a modest decrease that approaches statistical significance, this decrease was not statistically significant ( F (1,18) = 4.37, p = 0.051; Fig. 1 I ).

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