highly significantP = 0.03
Serum concentrations of all three biomarkers were higher in the high IgM responder group, but again total tau was the most highly significant difference [GFAP: 58.2 (32.6–87.05) versus 37.8 (23.8–43.1), P = 0.03; NfL: 7.5 (5.2–16.5) versus 4.6 (3.0–8.1), P = 0.026; total tau: 1.1 (0.9–1.3) versus 0.8 (0.7–0.9), P = 0.001; Fig. 3E ].