New Statement about NRF2 in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.

Biomolecules · 2022 · PMC9496161 · PMID 36139039

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However, a highly significant increase was observed in the expression levels of HO-1 ( Figure 5 E) and NQO1 ( Figure 5 F), supporting the idea that increased oxidative stress in the spinal cord activated the antioxidant machinery regulated by the NRF2 pathway.

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