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Global Burden, Regional Differences, Trends, and Health Consequences of Medication Nonadherence for Hypertension During 2010 to 2020: A Meta-Analysis Involving 27 Million Patients.

J Am Heart Assoc · 2022 · PMC9496433 · PMID 36056737

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a decreasing trendno p-value reported
Although a decreasing trend in nonadherence has been described in a few US studies, this trend has not been observed globally. 74 , 75 This suggests that, although evidence‐based interventions, such as reduction in daily number of pills and single‐pill combinations, can reduce medication nonadherence, they were not ad

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.