Clinical Characterization and Prognostic Value of TPM4 and Its Correlation with Epithelial-Mesenchymal Transition in Glioma.

Brain Sci · 2022 · PMC9497136 · PMID 36138856

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In tumor cells and macrophages, TPM4 expression showed an increasing trend as the WHO grade increased, suggesting that TPM4 abnormality was mainly attributed to tumor progression and tumor-associated macrophage (TAM) infiltration, which was further confirmed in the subsequent pseudotime trajectory analysis.

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