highly significantp < 0.0001
Based on the results of ANOVA, listed in the Supplementary Materials ( Table S1 ), the regression model for yield was highly significant ( p < 0.0001), and the obtained coefficient of determination R 2 value was 0.9868 with a non-significant lack of fit ( p = 0.0557), showing a reasonable representation between the input parameters and the observed extraction yield.