Preparation, Characterization and Pharmacokinetics of Tolfenamic Acid-Loaded Solid Lipid Nanoparticles.

Pharmaceutics · 2022 · PMC9503184 · PMID 36145677

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extremely significantno p-value reported

Through the fitted plots of the pharmacokinetic parameters, the C max of the commercially available TA injection was higher than that of the nanosuspension, but the other pharmacokinetic parameters, including T max , AUC 0–∞ , MRT 0–∞ , and T 1/2, were lower than those of the nanosuspension with extremely significant differences.

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