Safety and immune response kinetics of GRAd-COV2 vaccine: phase 1 clinical trial results.

However, while low and intermediate vaccine dose are associated to highly significant contraction at 6 months (Student t test for paired data w4/w24 L p = 0.0013, I p = 0.0008), it is not the case for high dose ( p = 0.0647), suggesting better persistence of neutralization activity with higher vaccine dose.

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