ECFC-derived exosomal THBS1 mediates angiogenesis and osteogenesis in distraction osteogenesis via the PI3K/AKT/ERK pathway.

J Orthop Translat · 2022 · PMC9513111 · PMID 36196150

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an increasing trendno p-value reported

Similarly, bone remodeling was assessed via Micro-CT, and the bone density (BMD values), BV/TV, Tb.Th, and Tb.N values in the canine mandibular distraction gap showed an increasing trend, with higher values observed in the shTHBS1-Exos group on DO42 ( Fig. 4 e-i).

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