Barely Significant
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Third dose of COVID-19 mRNA vaccine appears to overcome vaccine hyporesponsiveness in patients with cirrhosis.

J Hepatol · 2022 · PMC9519143 · PMID 36181987

Europe PMCDOI
1
hedged sentence
0.0010
closest p · 0.0× alpha
0.0010
boldest claim

The sentences

highly significantp = 0.001actually significant
The receipt of 3 doses of the BNT 162b2 mRNA vaccine was associated with a highly significant 96% reduction in COVID-19 infection (aHR 0.04, 95% CI 0.01-0.27, p = 0.001), a 91% reduction in symptomatic COVID-19 (aHR 0.01-0.71, p = 0.02), a 100% reduction in moderate, severe or critical COVID-19 (aHR 0.00, 95% CI 0.00-0.04, p < 0.001), and a 100% reduction in severe or critical COVID-19 (aHR 0.0, 95% CI 0.00-0.02, p < 0.001) compared to participants who received 2 doses ( Table 4 ).

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