The regression analysis of tear film urea and ST showed a linear progression with an r = 0.85 ( p < 0.001), inferring that the tear film urea decreases as Schirmer's wetting also decreases. The areas under the receiver operator characteristic curves (AUC) for tear film urea for diagnosing DED were highly significant.
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Evaluation of Tear Film Urea Level as a Diagnostic Marker of Dry Eye Disease: A Pilot Study.
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