Axial hypersensitivity is associated with aberrant nerve sprouting in a novel model of disc degeneration in female Sprague Dawley rats.

Also of note, 20 significant correlations were detected between selected outcomes including a moderate and highly significant correlation ( R = 0.59, p < 0.0004) between axial hypersensitivity and disc nerve sprouting.

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54 , 55 , 56 , 57 , 58 Sham animals consistently had higher withdraw thresholds than injured animals, but these differences failed to reach significance at all time points except for week 14 between sham and 1‐scrape.

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