Carbon dots conjugated to SN38 for improved colorectal anticancer therapy.

More importantly, the cells showed an apparent trend of recovery after 72 ​h only in the case of SN38, providing another piece of evidence of a slower release and, possibly, a persisting effect of the drug when loaded on CDs ( Fig. 4i–n, 4o-r, 4 s). 3.3 Cell cycle monitoring Encouraged by the cytotoxic effect of the CD-SN38 hybrid material, the mechanism of cytotoxicity was investigated via the analysis of the cell cycle.

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