Reappraisal of screening strategy in hepatitis B surface antigen-negative blood donors: Correlation with hepatitis B virus-DNA quantification.

In a population with a high prevalence of infection, the number of blood donors with evidence of natural, resolved infection is likely to be significant, resulting in the potentially unnecessary discard of many blood donations.[ 24 ] The donor loss caused by universal anti-HBc screening was considered sustainable in low-endemic countries, though, it is generally admitted that, rejecting anti-HBc reactive blood would severely affect blood supply in medium-to-high endemic areas like Bangladesh where the prevalence of anti-HBc is high (11.7%–22.6%).[ 18 , 20 ] Moreover, it gives inaccurate information on HBV infection among rejected donors.

also in 1,824 other papers