Clinical and Prognostic Impact of Copy Number Alterations and Associated Risk Profiles in a Cohort of Pediatric B-cell Precursor Acute Lymphoblastic Leukemia Cases Treated Under ICiCLe Protocol.

Hemasphere · 2022 · PMC9529051 · PMID 36204689

Europe PMC DOI

hedged sentences

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closest p · 0.0× alpha

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boldest claim

The sentences

highly significantP < 0.001actually significant

7 , 25 – 27 A highly significant correlation of IKZF1 deletion (n = 96) was noted with high TLC ( P < 0.001), NCI-HR ( P < 0.001), induction failure ( P < 0.001), and ICiCLe-HR ( P < 0.001) with primary genetic HR group ( P < 0.001).

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borderline significantno p-value reported

IKZF1 deletions had statistically poor EFS and high RR in the ICiCLe-IR group but was borderline significant in the ICiCLe-HR group.

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