Barely Significant
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KP372-1-Induced AKT Hyperactivation Blocks DNA Repair to Synergize With PARP Inhibitor Rucaparib <i>via</i> Inhibiting FOXO3a/GADD45α Pathway.

Front Oncol · 2022 · PMC9530825 · PMID 36203459

Europe PMCDOI
1
hedged sentence
0.0040
closest p · 0.1× alpha
0.0040
boldest claim

The sentences

highly significantP = 0.004actually significant
We tested drug-drug interactions for three pairs: KP372-1 + rucaparib, KP372-1 + olaparib, and KP372-1 + talazoparib, all of which showed highly significant effect of synergy (η = 0.472, P = 0.004; η = 0.453, P = 0.002; η = 0.613, P = 0.009, respectively).

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