A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation.

Cell Rep · 2022 · PMC9549417 · PMID 36170819

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highly significantno p-value reported

Furthermore, our nuclear sAC model leads to changes in gene expression that exhibit a highly significant inverse correlation with YAP-dependent gene expression across a large panel of 45 human melanoma cell lines.

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