Barely Significant
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Time evolution of cytokine profiles associated with mortality in COVID-19 hospitalized patients.

Front Immunol · 2022 · PMC9551198 · PMID 36238287

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an increasing trendno p-value reported
In addition, whereas no trend is observed in PC1 or PC3, PC2 seems to display an increasing trend through time.

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a decreasing trendno p-value reported
On the other hand, BDNF, IL-12 and IL-15 (PC1) are significantly reduced in non-survivors at all time points with a decreasing trend through time, though a protective factor.

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.