High phenylalanine concentrations induce demyelination and microglial activation in mouse cerebellar organotypic slices.

Front Neurosci · 2022 · PMC9559601 · PMID 36248632

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We confirmed that these conditions resulted in a highly significant, over twofold reduction in MBP signal ( t (18) = 6.16, P < 0.001, Figures 2B,Ea,d ) and in a trend toward a decrease in calbindin staining ( t (18) = 2.03, P = 0.06, Figures 2C,Eb,e ).

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